<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="../nsu_article.xsl"?><!DOCTYPE nsuarticle PUBLIC "-//NPG//DTD NSU//EN" "nsu_article.dtd"><nsuarticle type="news">   <articleidlist>      <articleid type="uid">010426</articleid><storyno>-15</storyno>      <articleid type="doi">10.1038/nsu010426</articleid><storyno>-15</storyno>   </articleidlist>   <pubfm>      <confgrp color="">         <confdate></confdate>         <confplace></confplace>         <conftitle></conftitle>      </confgrp>      <pubdate>         <dayofweek name="Thursday"></dayofweek>         <day>26</day>         <month>April</month>         <year>2001</year>      </pubdate>      <category>brain</category>   </pubfm>   <fm>      <title>To sleep, perchance to learn</title>      <aug><fnm>John</fnm><snm>Whitfield</snm></aug>      <standfirst>A good night's sleep might be the best way to let the brain file the day's events.</standfirst>   </fm>   <body><p><figure filename="sleeping_200.jpg" align="right"><caption>Sleeping on it really may be the best way to learn.</caption><source></source></figure></p>      <p>Baby birds and mammals sleep for up to three times as long as adults.         New research suggests that this may be to allow their brains to adapt         to the riot of novelty they experience.</p>      <p>Michael Stryker, of the University of California, San Francisco, found         that the amount of change in the brains of young cats placed in a new         environment was tightly linked to the amount of slow-wave sleep -- the         non-dreaming state -- the cats got<bibr rid="b1">1</bibr>.</p>      <p>This link is a surprise, says Stryker, as dreams, also known as rapid         eye-movement (REM) sleep, are often thought of as the brain's way of replaying         and analysing the day's experiences.</p>      <p>"The finding that the benefit of sleep seems to lie in non-REM sleep         is very interesting," says Jim Horne, a sleep researcher at the University         of Loughborough, UK. "REM sleep has been seen as important in the maturation         of the brain."</p>      <p>Chemicals released during sleep might remodel the brain by stimulating         and inhibiting neural growth, Stryker says. Many hormones, such as testosterone         and growth hormone, are released at night, and he suspects that nocturnal         chemical signals "may really play a crucial role in consolidating and         enhancing waking experience".</p>      <p>The team studied young cats, whose brains are developing rapidly and         are particularly sensitive to environmental change. The researchers covered         one of the cats' eyes for six hours. This causes the brain's visual cortex         to weaken its response to the image from the covered eye, and up its commitment         to the active eye.</p>      <p>When cats slept for six hours after the test period, the amount of change         in their neural responses was double that of cats denied a nap<bibr rid="b1">1</bibr>.         Sleepers' brains changed more even than those of cats that spent an extra         six hours with one eye covered.</p>      <p>Might this be a general function of sleep? Can we extrapolate from developing         cats to fully formed humans, and from the visual system to other forms         of mental adaptation?</p>      <p>Stryker thinks so: "We wanted to ask whether, for example, studying for         an exam and then sleeping is as effective a way of learning as pulling         an all-nighter." These results, he says, suggest that the route to an         A-grade passes through the Land of Nod.</p>      <p>Psychologist Carlyle Smith, of Trent University, Ontario, Canada, studies         how sleep affects human learning and memory. He agrees that similar neural         changes might occur in the sleeping human brain after new experience.</p>      <p>In his experiments, Smith too has seen a link between slow-wave sleep         and people's ability to learn repetitive but delicate and precise patterns         of movement -- of the type that "might be important for sports people or         musicians".</p>      <p>"If we train people on a task, we find that if we interrupt their [slow-wave]         sleep, they don't remember how to do it," Smith says.</p>         </body>   <bm>      <refgrp>         <bib id="b1"><refau><snm>Frank</snm>, <fnm>M. G.</fnm></refau>, <refau><snm>Issa</snm>, <fnm>N. P.</fnm></refau> &amp; <refau><snm>Stryker</snm>, <fnm>M. P.</fnm></refau> <atl>Sleep enhances plasticity in the developing visual cortex.</atl> <jtl>Neuron</jtl> <vol>30</vol>, <spn>1</spn>-<epn>20</epn> (<pubyear>2001</pubyear>).</bib>      </refgrp>   </bm></nsuarticle>
